

Painkiller Jane
Painkiller Jane is an American-Canadian science fiction and action television series based on the comic book character of the same name. Airing on the Sci Fi Channel in the US starting April 13, 2007 and Global in Canada, it starred Kristanna Loken as the titular character. On August 15, 2007, it was canceled after one season of 22 episodes.
Where to watch Painkiller Jane in United States
Click a service to open Painkiller Jane there. Availability last verified on June 20, 2026.
Where is Painkiller Jane streaming around the world?
| Country | Streaming on | Rent / Buy |
|---|---|---|
| United States | The CW, The Roku Channel, Plex, Tubi TV | Amazon Video, Apple TV Store, Fandango At Home |
| United Kingdom | — | Amazon Video |
| Australia | — | Apple TV Store |
About Painkiller Jane
Painkiller Jane is a 2007 English-language sci-fi & fantasy and action & adventure series created by Gil Grant. The cast is led by Kristanna Loken, Rob Stewart, Noah Dalton Danby. It spans 1 season and 22 episodes and has concluded. Viewers rate it 6.0/10 across 100 ratings. In United States, it is currently streaming on The CW, The Roku Channel, Plex.
Painkiller Jane was produced by Insight Film Studios and Insight Films and made in Canada and United States of America. It was first aired on April 13, 2007, and carries a TV-MA certification.
- Created by
- Gil Grant
- First aired
- April 13, 2007
- Last aired
- September 21, 2007
- Original language
- English
- Age rating
- TV-MA
- Status
- Ended
- Seasons
- 1 (22 episodes)
- Network
- Syfy, Global TV
- Country
- Canada, United States of America
- Production
- Insight Film Studios, Insight Films
Painkiller Jane cast & crew
Painkiller Jane was created by Gil Grant.
The cast features Kristanna Loken as Jane Vasco, Rob Stewart as Andre McBride, Noah Dalton Danby as Connor King, Stephen Lobo as Seth Carpenter, and Sean Owen Roberts as Riley Jensen.
Behind the camera, it was produced by Lawrence Hertzog and Kristanna Loken.
Is Painkiller Jane worth watching?
Painkiller Jane holds an audience score of 6.0/10 from 52 ratings, a more divisive sci-fi & fantasy series.
With 1 season and 22 episodes, it's a meaty weekend watch.
If you enjoy sci-fi & fantasy and action & adventure, Painkiller Jane is worth a place on your watchlist.
How and where to watch Painkiller Jane
In United States, you can stream Painkiller Jane on The CW, The Roku Channel, Plex, and Tubi TV, or rent and buy it on Amazon Video, Apple TV Store, and Fandango At Home. Click any service above to open it directly.
Streaming rights change country by country and month by month, so the options above reflect United States today — switch your country at the top of the where-to-watch section to see availability elsewhere.
Rate & review
Your rating and review are saved privately in this browser — no account needed.
Cast of Painkiller Jane

Kristanna Loken
Jane Vasco

Rob Stewart
Andre McBride

Noah Dalton Danby
Connor King

Stephen Lobo
Seth Carpenter

Sean Owen Roberts
Riley Jensen
Painkiller Jane — FAQs
▸Where can I watch Painkiller Jane in United States?
Painkiller Jane is streaming on The CW, The Roku Channel, Plex, Tubi TV in United States.
▸Is Painkiller Jane on The CW?
Yes — Painkiller Jane is currently available on The CW in United States.
▸What language is Painkiller Jane in?
Painkiller Jane is originally in English. Subtitle and dub options vary by streaming service.
▸How many seasons of Painkiller Jane are there?
Painkiller Jane has 1 season with 22 episodes in total.
▸What is Painkiller Jane rated?
Painkiller Jane is rated TV-MA. It holds a 6.0/10 audience score from 52 ratings.











